Translating Clinical Trials into Meaningful Outcomes
نویسندگان
چکیده
منابع مشابه
Translating clinical trials into meaningful outcomes.
Efforts to unravel the complex biology that is necessary to develop new therapies best suited for an individual with cancer are at a crossroads with a strained health care system and an insufficient clinical trial apparatus. The resulting failures have been described as the "valley of death." Progress into the future will require new considerations and the engagement of a broad band of stakehol...
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Biology has long been recognized as an excellent source of analogies and stimuli for engineering design. Previous work focused on the systematic identification of relevant biological analogies by searching for instances of functional keywords in biological information in natural language format. This past work revealed that engineering keywords couldn’t always be used to identify the most relev...
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It is well established that exercise elicits a finely tuned adaptive response in skeletal muscle, with contraction frequency, duration, and recovery shaping skeletal muscle plasticity. Given the power of physical activity to regulate metabolic health, numerous research groups have focused on the molecular mechanisms that sense, interpret, and translate this contractile signal into postexercise ...
متن کاملProgesterone and preterm birth prevention: translating clinical trials data into clinical practice
0002-9378/free © 2012 Published by Mosby, Inc. OBJECTIVE: We sought to provide evidenc the prevention of preterm birth (PTB). METHODS: Relevant documents, in part PubMed (US National Library of Medicine, 19 in English, which evaluate the effectiveness o gens evaluated were, in particular, vaginal pr caproate. Additionally, the Cochrane Library, through review of the above were utilized to accor...
متن کاملProgesterone and preterm birth prevention: translating clinical trials data into clinical practice.
OBJECTIVE We sought to provide evidence-based guidelines for using progestogens for the prevention of preterm birth (PTB). METHODS Relevant documents, in particular randomized trials, were identified using PubMed (US National Library of Medicine, 1983 through February 2012) publications, written in English, which evaluate the effectiveness of progestogens for prevention of PTB. Progestogens e...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2010
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-10-2632